Known to Trekkies as the omnipotent Q in "Star Trek" and to soap opera fans as Eugene from "Days of our Lives", John de Lancie was brought on to play the villain, Discord in a 2011 episode of "My Little Pony: Friendship is Magic". Show creator Lauren Faust admits the character was written with the character of Q in mind.

Five days before his death, acclaimed director and actor Orson Welles completed voice work in the 1986 film, "Transformers: The Movie". Quoted on his character, "You know what I did this morning? I played the voice of a toy. I play a planet. I menace somebody called Something-or-other. Then I'm destroyed. My plan to destroy Whoever-it-is is thwarted and I tear myself apart on the screen."

Before playing Deputy James Garcia on "Reno 911", Carlos Alazraqui would voice the titular character of "Rocko's Modern Life" as well as a few other minor characters in the show, including Rocko's dog, Spunky.

Gabriel Damon played the adorable Littlefoot in the classic film, "The Land Before Time". He would also play that little shit, Hob in "Robocop 2".

In 2002 Daveigh Chase would play both Lilo in DIsney's "Lilo and Stich" and Samara Morgan in "The Ring

After playing Wash on Firefly, Alan Tudyk went on to play King Candy in the Disney film, "Wreck it Ralph". Disney also brought him back for 2013's "Frozen" where he played The Duke of Weselton.

In one of his final roles before his death, Phil Hartman supplied the English voice of the cat Jiji in the Hayao Miyazaki film, "Kiki's Delivery Service".

Leonard Nimoy wasn't the only actor from the Trek TV series to work on 2009's "Star Trek". Wil Wheaton was brought on during post-production to record some voiceover lines for a few of the Romulan crew members.

Acclaimed stage actor, Derek Jacobi, who "Doctor Who" fans might recognize from his role as Professor Yana The Master also played Nicodemus in the classic animated film, "The Secret of Nimh". Whovians might also be interested to know he played The Master in several audio plays for Doctor Who prior to the series reboot in 2005.

You might remember him as Artie, the strongest man in the world, from the Nickelodeon cult classic, "The Adventures of Pete and Pete". In the 2000's he would voice both Cotton Hill and Kahn Souphanousinphone in "King of the Hill"